TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.0340nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.0780nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex...More data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.166nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.214nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.266nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.576nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.628nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.640nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.760nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human MTAP assessed as reduction in methylthioadenosine phosphorolysis/hydrolysisMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1.39nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1.70nM ΔG°: -11.8kcal/molepH: 7.0 T: 2°CAssay Description:Enzyme activity was monitored by absorbance change in the xanthine oxidase coupled assay, which measures the formation of 2,8-dihydroxyadenine at 293...More data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 2nM ΔG°: -11.7kcal/molepH: 7.0 T: 2°CAssay Description:Enzyme activity was monitored by absorbance change in the xanthine oxidase coupled assay, which measures the formation of 2,8-dihydroxyadenine at 293...More data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of human MTAP as initial dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of human MTAP as equilibrium dissociation constantMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Inhibition of His-tagged human MTAPMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair